This week, we’re diving deep into the fascinating world of ketone supplementation with Dr. Gus Vickery.

Dr. Vickery unpacks the complex physiology of ketone metabolism, explains who might benefit most from supplementation, and shares evidence-based insights from both research and clinical practice.

Whether you’re an athlete looking to optimize performance or just curious about the science behind ketones, this episode breaks down everything you need to know about how these supplements work in your body.

What can these magic molecules do for sleep and improving cognition—well tune in and find out!!!

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Guest Biography

Dr. Gus Vickery

Dr. Gus Vickery

Dr. Gus Vickery is a board-certified family physician who specializes in personalized health consultations focused on total body and mind optimization.
He is also a speaker and the author of Authentic Health (May 2018, MJ Publishing).

He founded Authentic Health in 2005 which has grown to multiple medical providers serving in 2 locations including The Clinic at Biltmore, an innovative direct to employer clinic for The Biltmore Company.

Dr. Vickery offers personalized health consultations both virtually and in-person at his office in Asheville, NC. He uses advanced biometrics, genetics, hormonal assessments, metabolic and nutritional assessments, and other advanced diagnostics to determine the proactive and comprehensive strategies that will help his clients experience their best health and lifespan.

He is an expert in the use of peptides, targeted supplementation, and hormonal optimization to potentiate an individual’s best health. More information is available at www.drgusvickery.com and www.authentichealth.com

Dr. Vickery is an honor graduate of the Medical College of Georgia. He is a member of the Alpha Omega Alpha honor medical society, and teaches medical students for the department of family medicine of The University of North Carolina at Chapel Hill. He has served as president of the Western North Carolina Medical Society.

Show Notes from this episode

  • Introduction to Dr. Gus Vickery and Ketone Supplementation 0:00
    • Dr. Barrett introduces Dr. Gus Vickery, highlighting his expertise in biohacking and metabolism.
    • Dr. Vickery explains his practice in Asheville, North Carolina, and his background in family medicine.
    • Dr. Vickery discusses his journey from traditional family medicine to focusing on nutritional biochemistry and molecular biology.
    • He shares his observations on the health of his patients and his shift towards addressing upstream causes of diseases.
  • Dr. Vickery’s Approach to Health and Disease 3:44
    • Dr. Vickery describes his approach to health, emphasizing lifestyle changes, nutritional deficiencies, and simple interventions.
    • He explains the tools his clinic uses to assess human health, including DEXA, toxicant assessment, and mitochondrial function tests.
    • Dr. Vickery discusses the importance of understanding the environment and food habits that affect human health.
    • He highlights the success of his clinic in stabilizing and reversing metabolic diseases through comprehensive health assessments.
  • The Power of Human Physiology and Preventive Medicine 6:46
    • Dr. Barrett shares a patient success story, emphasizing the power of human physiology in recovery.
    • Dr. Vickery and Dr. Barrett discuss the importance of addressing the root causes of health issues rather than just treating symptoms.
    • Dr. Vickery talks about restoring confidence in the body and helping patients understand the underlying causes of their health problems.
    • They highlight the role of environmental factors and nutritional deficiencies in health issues.
  • Ketone Supplementation and Its Benefits 12:10
    • Dr. Barrett shares his experience with ketone supplements and their impact on performance and effortlessness during workouts.
    • Dr. Vickery explains the difference between being ketogenic and using ketones, and the role of ketone bodies in energy production.
    • He discusses the benefits of ketones in reducing oxidative stress and improving mitochondrial efficiency.
    • Dr. Vickery highlights the potential of ketones in enhancing brain and heart health, especially in conditions like traumatic brain injuries and cardiomyopathies.
  • Ketone Salts vs. Ketone Esters 24:12
    • Dr. Vickery explains the difference between ketone salts and ketone esters, emphasizing the superiority of esters.
    • He discusses the challenges of ketone salts, including high salt loads and gastrointestinal distress.
    • Dr. Vickery explains the bioavailability and effectiveness of ketone esters in achieving ketosis.
    • He mentions the importance of measuring ketone levels to understand the body’s response to supplementation.
  • Applications of Ketone Supplements 39:48
    • Dr. Vickery discusses the various applications of ketone supplements, including performance enhancement, sleep improvement, and recovery.
    • He explains the optimal dosing for different purposes, such as pre-workout, post-workout, and bedtime doses.
    • Dr. Vickery highlights the benefits of ketones in reducing mental fatigue and enhancing cognitive performance.
    • He mentions the potential of ketones in improving recovery and reducing inflammation after workouts.
  • Ketones and Neurodegenerative Diseases 40:32
    • Dr. Vickery discusses the potential benefits of ketones in managing neurodegenerative diseases and traumatic brain injuries.
    • He shares his thoughts on using ketones as part of a protocol for post-concussion or post-traumatic brain injury recovery.
    • Dr. Vickery emphasizes the importance of ketones in maintaining brain health and reducing oxidative stress.
    • He suggests considering ketones for individuals with conditions like Alzheimer’s, Parkinson’s, and multiple sclerosis.
  • Ketones in Sports Performance and Recovery 43:14
    • Dr. Vickery discusses the potential of ketones in enhancing sports performance and reducing mental mistakes.
    • He highlights the benefits of ketones in improving endurance and reducing fatigue in athletes.
    • Dr. Vickery mentions the importance of combining ketones with carbs for optimal performance in high-intensity workouts.
    • He suggests using ketones as a replacement for caffeine for mental alertness and focus.
  • Ketones for Weight Management and Fever Management 48:50
    • Dr. Vickery explains the role of ketones in managing hunger and cravings during low-calorie diets.
    • He discusses the benefits of ketones in reducing the impact of hunger signals and aiding in weight management.
    • Dr. Vickery mentions the potential of ketones in managing fever and reducing the need for caffeine.
    • He emphasizes the importance of individualized dosing and monitoring ketone levels for optimal results.
  • Conclusion and Final Thoughts 50:11
    • Dr. Barrett and Dr. Vickery summarize the key points discussed in the conversation.
    • Dr. Vickery reiterates the importance of ketones in enhancing performance, recovery, and brain health.
    • They discuss the potential of ketones in various health applications and the importance of individualized approaches.
    • Dr. Barrett thanks Dr. Vickery for the insightful conversation and looks forward to future discussions.

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