Samuel Shepherd

00:00 – Introduction

Dr. Barrett welcomes listeners and introduces this as a continuation of last week’s conversation with Samuel Shepherd about astaxanthin’s antioxidant properties and ability to reduce high-sensitivity CRP (hsCRP) values.

• Discussion of his unique “n of one” experiment developing astaxanthin therapy
• Announcement of sponsor code: valasta.net with code POI5 for 5% discount
• Episode topics preview: reactive oxygen species (ROS), inflammation, disease processes

01:21 – Astaxanthin’s Unique Glucose Attachment (The “Trojan Horse” Mechanism)

Samuel explains how ValAsta differs from other astaxanthin supplements:

• Natural form: In algae, astaxanthin exists with glucose chemically attached (glucosidic/liposomal form)
• Standard extraction problem: Supercritical CO2 extraction removes glucose, reducing absorption to 1/8 of the natural form
• ValAsta’s solution: Patented process to reattach glucose to astaxanthin for superior absorption

02:19 – How the Glucose Attachment Works

• Glucose attachment allows astaxanthin to pass through the gut barrier
• Pharmaceutical industry commonly uses glycosides/glucosides for improved drug absorption
• Samuel references his background in chemical weapons development where “Trojan horse” delivery systems were used

02:24 – Cancer Cell Targeting Mechanism

The Trojan Horse Effect:

• Cancer cells have massive metabolic consumption (16x more sugar than normal cells)
• Hydroxyl free radicals generated by cancer metabolism create acidic environment (pH 5.2)
• Cancer cells aggressively pull in glucose-attached astaxanthin
• Once inside, enzymes break off glucose
• Free astaxanthin neutralizes hydroxyl free radicals (OH⁰ → OH⁻¹)
• OH⁻¹ has pH of 11, which kills cancer cells in 4 seconds through saponification of cell membrane

07:05 – Cancer Marker Spike Phenomenon

• CA-125, CA 19-9 markers initially spike dramatically when cancer cells die
• This alarmed oncologists who thought cancer was becoming more aggressive
• Markers drop back to normal within 4 days as cell debris clears
• The spike represents dead cancer cell antigens flooding bloodstream, not cancer growth

07:46 – Dosing Protocol & hsCRP Testing

Step 1: Get baseline hsCRP tested
Dosing guidelines:

• hsCRP 2.5-3.0 mg/L: 0.1 mg per kg body weight (e.g., 70 kg person = 7-10 mg/day)
• hsCRP under 2.0 mg/L: May not need astaxanthin supplementation
• hsCRP over 3.0 mg/L: Higher therapeutic doses needed
• Severe cases: Working with patients with hsCRP of 80+ (typically cancer, heart disease)

08:01 – Additional Inflammatory Markers

Beyond hsCRP, sed rate (ESR) is monitored as secondary marker for inflammation tracking.

08:16 – The “Tree” Model of Disease

Samuel explains his conceptual framework:

• Roots: Causes of ROS (diet, stress, sugar, fructose, smoking, heavy metals, pollution)
• Trunk: Reactive oxygen species (ROS) – the common pathway
• Branches: Different disease manifestations (arthritis, cancer, diabetes, Alzheimer’s, Parkinson’s, heart disease)
• Treatment philosophy: Cut the tree at the trunk (eliminate ROS) rather than treating individual branches (symptoms)

10:57 – Comparative Antioxidant Power

Astaxanthin has significantly more antioxidant capacity than glutathione (considered the “mother of all antioxidants”) and vitamin C.

13:09 – The Importance of Baseline Testing

Before purchasing astaxanthin, get hsCRP tested to establish baseline and determine if supplementation is needed.

13:26 – Cholesterol Myth & Heart Disease

• Misconception: Cholesterol causes heart disease
• Reality: Arterial inflammation causes heart disease
• Cholesterol attempts to heal arterial lesions but forms problematic scabs (plaques)
• hsCRP over 3 mg/L is strong predictor of cardiovascular disease

16:44 – Samuel’s Personal Cardiac Story

Dr. Radislav Stephan Kais (inventor of coronary stent) performed catheterization on Samuel at age 70:

• Finding: Severe systolic kink in LAD (left anterior descending artery) – congenital defect
• Every heartbeat caused mini heart attack due to artery kinking
• Dr. Kais’s prognosis: 30-35 more years of life expectancy despite defect
• Key finding: Zero inflammatory disease anywhere in vascular system at age 70

21:11 – Samuel’s Wife’s Cardiac Results

• Lifetime cholesterol levels of 260-280 (unmedicated)
• Dr. Kais’s finding: “Coronary health of a 20-year-old”
• Zero arterial inflammation despite elevated cholesterol
• This challenged conventional cardiology wisdom about cholesterol

21:22 – West Virginia/Arkansas Genetics Joke

Dr. Kais ruled out genetics as explanation unless there was inbreeding (humorous moment).

21:46 – Dr. Kais’s Response

After seeing Samuel and wife’s results:

• Immediately put all staff on ValAsta
• Now prescribes ValAsta to all coronary patients
• This represents validation from leading interventional cardiologist

22:24 – Brain Cholesterol vs. Heart Cholesterol Paradox

• Brain is 70% cholesterol and needs it for function
• Cardiology pushes to lower cholesterol to 150 for heart health
• Neurology warns this will damage brain function
• The disconnect: Cholesterol isn’t the problem – inflammation is

23:35 – 92% of Disease Deaths Are Inflammatory

Samuel emphasizes that 92% of all disease-related deaths (excluding accidents) are inflammatory in origin.

23:59 – Legal Challenges

Samuel faced two complaints for “practicing medicine without a license”:

• Oregon and Texas medical boards filed complaints
• Both withdrawn when boards understood the biochemistry and patent
• Patent title: “Method for the process of using astaxanthin to treat inflammatory disease, particularly for the treatment of cancer”
• FDA dislikes words: treat, cure, diagnose

24:08 – The Oncologist’s Call

Female oncologist contacted Samuel about 8 stage IV cancer patients:

• All in hospice (2-4 weeks to live)
• All started taking ValAsta independently
• Cancer disappeared in all 8 patients
• Common denominator: All were taking ValAsta
• Her real reason for calling: Her husband diagnosed with stage IV prostate cancer

26:28 – Oncologist’s Shocking Statement

“Nobody in my family is doing chemo or radiation.”
This statement from a practicing oncologist reveals the treatment crisis in conventional oncology.

26:34 – Her Husband’s Results

• PSA dropped from 20s to under 3
• Age 68, now in remission
• Note: Prostatitis can also elevate PSA, not just cancer

26:28 – Limitations of Medical Imaging

PET scans, CAT scans, and MRIs with contrast cannot differentiate between inflammatory lesions and cancer because both light up the same way.

27:17 – Biopsy Risks

Needle biopsies risk breaking open tumors and allowing cancer cells to spread throughout the body.

29:20 – Upstream Intervention Philosophy

IL-1, IL-6, NF-kappa-beta are all results of free radical attack. Astaxanthin works one step earlier by eliminating the hydroxyl and superoxide radicals that trigger these cytokines.

29:20 – The Parkinson’s Disease Case

82-year-old woman in Hershey, Pennsylvania:

• Initial reason for taking astaxanthin: Arthritis treatment
• Unexpected result: Severe Parkinson’s tremors completely stopped
• Could not hold food on fork; daughter had to feed her
• After astaxanthin: All tremors ceased

31:29 – Parkinson’s Disease Mechanism Revelation

Medical dogma: Parkinson’s is caused by lack of dopamine production in substantia nigra
Reality Samuel discovered:

• Substantia nigra produces huge amounts of dopamine
• Dopamine reacts with hydroxyl free radicals → forms hydroxydopamine
• Hydroxydopamine is the actual toxin that causes Parkinson’s symptoms
• Ironically, hydroxydopamine is what researchers give to animals to induce Parkinson’s for drug testing

32:03 – The Dopamine/Hydroxyl Reaction

Chemical equation: Dopamine + Hydroxyl free radical → Hydroxydopamine

Parkinson’s patients have low dopamine-to-hydroxydopamine ratio because all dopamine is being converted.

34:53 – Standard Parkinson’s Treatment Failure

• Medical system gives levodopa or carbidopa to increase dopamine
• This temporarily improves symptoms
• But doesn’t address hydroxyl radicals
• Eventually hydroxyl concentration neutralizes the extra dopamine
• Patients become resistant and die from Parkinson’s
• Astaxanthin approach: Eliminate hydroxyl radicals, stopping the conversion reaction

34:53 – Estrogen and Breast Cancer Truth

Medical dogma: Estrogen causes breast cancer; use estrogen-blocking drugs
Reality:

• If estrogen caused cancer, 16-30 year old women (peak estrogen) would all have cancer
• Actual mechanism: Estrogen + Hydroxyl free radical → Dihydroxyestradiol
• Dihydroxyestradiol is the known carcinogen, not estrogen
• Standard treatment reduces estrogen (wrong target)
• Astaxanthin approach: Remove hydroxyl radical, preventing carcinogen formation

34:53 – Testosterone and Prostate Cancer Parallel

Same mechanism as estrogen:

• Testosterone + Hydroxyl free radical → Hydroxytestosterone
• Hydroxytestosterone causes cancer, not testosterone itself
• Medical system chemically castrates men by reducing testosterone (wrong target)
• Should eliminate hydroxyl radicals instead

35:16 – Why Young People Don’t Get These Diseases

Young people have sufficient glutathione, catalase, and superoxide dismutase to neutralize free radicals, preventing these hydroxylated compounds from forming.

36:20 – The Infertility Crisis Discussion

Dr. Barrett raises concern about current testosterone levels in young men:

• Normal testosterone in young men now averages 200-300 (dramatically low)
• Fertility rates dropping
• Question: Could mRNA technology be causing hydroxylation of testosterone and estrogen?

37:42 – COVID-19 Bioweapon Evidence

Samuel wrote paper to President Trump in March 2021 detailing 8 protocols proving COVID-19 was man-made:

The Genetic Proof:

• Natural RNA has “start codon” (AUU – Adenosine, Uracil, Uracil)
• Ribosome searches along RNA until finding AUU sequence to begin protein synthesis
• Ends at “stop codon” (AUG – Adenosine, Uracil, Guanine)
• In natural RNA, start codon appears randomly, often midway through sequence
• COVID-19 RNA: Start codon was first three nucleotides
• Statistically impossible in nature
• Scientists wanted maximum efficiency with minimal wasted genetic material
• This proves intentional, synthetic construction

42:58 – Craig Venter’s Synthetic Organism

Dr. Craig Venter created synthetic DNA organism in San Diego laboratory that has been living since 2008 – proof that synthetic life can be created.

42:58 – The mRNA Vaccine Problem

• Human body lacks enzymes to break down synthetic RNA from vaccines
• RNA persists in body, constantly producing antigens and proteins
• Accumulates in capillary-rich areas: kidneys (glomerulus), testicles, heart
• Causes myocarditis by inflaming small cardiac capillaries
• Creates “yellow gooky material” extractable from arteries (genetic material from RNA)
• Triggers hyperactive inflammatory response (IL-6, IL-1)
• Cannot be degraded or eliminated by body

43:41 – Molten Aluminum Accident (Samuel’s Personal Story)

September 19, 2024:

• Watching aluminum being poured into mold
• Mold contained residual water drop
• Explosion wrapped molten aluminum around Samuel’s arm
• Third-degree burns
• No hospital visit – treated exclusively with topical astaxanthin

Treatment protocol:

1. Applied astaxanthin oil directly to burns
2. Applied Neosporin (topical antibiotic)
3. Wrapped in white cloth
4. Covered with Saran wrap
5. Left for 2 days without changing

Results:

• Melted polyester shirt off body
• Burned all hair from under arm
• Skin blown out from pressure
• Complete healing in 6 weeks with no scarring
• No infection
• Would have required burn unit and skin grafts with conventional treatment

46:17 – Pain Management & Healing Mechanism

• Second night had most severe pain (nerve endings burned)
• Astaxanthin didn’t eliminate inflammation (needed for healing)
• Instead, modulated inflammation to physiologic, manageable levels
• This prevented excessive tissue damage while allowing proper healing

47:21 – Engineering Equation for Free Radical Balance

Rate In – Rate Out = Accumulation

• Rate of free radical introduction (diet, stress, environment)
• Minus rate of free radical neutralization (antioxidants)
• Equals accumulation (inflammation level in body)

Astaxanthin increases the “Rate Out” term, allowing accumulation to drop even while still introducing some free radicals.

48:19 – The Serendipity of Samuel’s Journey

Dr. Barrett reflects on how Samuel’s personal diagnosis led him to investigate:

• Which animals don’t get cancer?
• Why don’t they get cancer?
• How can this be applied to humans?

Most patients don’t have the biochemical engineering background to pursue this investigation.

49:05 – Global Impact

• ValAsta now in 26 countries
• International offices established
• No traditional sales or marketing – spread entirely through social media and word-of-mouth
• Cancer patients tell everyone when their cancer disappears
• “This all happened in our lifetime” (regarding social media)

49:41 – Future Book Project

Samuel mentions plans to write a book about his journey and discoveries.

50:00 – Contact Information

Website: ValAsta.net (V-A-L-A-S-T-A.net)
Phone: 803-470-1913
Support: Nurses available to guide through protocol at no charge
Philosophy: No consulting fees – most patients are financially drained by medical treatments

50:43 – Closing Thoughts

Samuel: “God keeps us around for a purpose.”
Recognition that his near-death diagnosis led to discovery that’s now helping thousands globally.

Key Takeaways:

1. Astaxanthin absorption: Glucose attachment (ValAsta’s patent) increases absorption 8x
2. Cancer mechanism: Trojan horse delivery kills cancer cells by raising intracellular pH to 11
3. Inflammation is the root: 92% of disease deaths are inflammatory
4. Test first: Get hsCRP before supplementing
5. Parkinson’s breakthrough: Not dopamine deficiency but hydroxydopamine toxicity
6. Hormone truth: Not estrogen/testosterone causing cancer but hydroxylated versions
7. COVID evidence: Genetic proof of synthetic origin
8. mRNA persistence: Body cannot break down synthetic RNA
9. Burn healing: Third-degree burns healed in 6 weeks with topical astaxanthin
10. Global impact: 26 countries, no marketing, word-of-mouth success

Discount Code: valasta.net with code POI5 for 5% discount

Related Episodes: Season 8, Episode 3 (Part 1 of this conversation)

Special Offer: Save 15% Using Code “SBPOD” At Checkout

Special Offer: Save 15% Using Code “SBPOD” At Checkout