Dr. Goodenowe’s research into the biochemical mechanisms of disease started in 1990. His curiosity about the biochemistry of life is as insatiable today as it was 30 years ago. In those 30 years, Dr. Goodenowe invented and developed advanced diagnostic and bioinformatic technologies, designed and manufactured novel and natural biochemical precursors, and identified biochemical prodromes of numerous diseases including Alzheimer’s disease and dementia, Parkinson’s disease, multiple sclerosis, stroke, autism, amyotrophic lateral sclerosis (ALS), schizophrenia, bipolar disorder, depression, and cancers of the colon, pancreas, ovary, breast, lung, kidney, liver, stomach, and others. And he is just getting warmed up. Dr. Goodenowe is now going beyond disease and the detection of biochemical dysfunctions to diagnose and the correction of biochemical dysfunctions to treat disease. Dr. Goodenowe’s new focus is to defeat the entropy of aging by creating strategic biochemical and biofunctional reserve capacity in advance of known disease risks such that the human body can maintain the physical and biological functions of life indefinitely and without disease.
Dr. Barrett 00:31 Introduction of Dr. Goodenowe
Dr. Goodenowe is a neuroscientist and synthetic organic chemist and a biochemist. And one of the
Dr. Goodenowe 03:49 Talks about his journey to now! And mass spectrometry re-invented
Dr. Goodenowe 12:59 Plasmalogens, Gastrointestinal tract acids, and age and disease association
Dr. Barrett 15:54 Discusses APOE4
Dr. Goodenowe 16:30 What are plasmalogens and what do they do?
Dr. Barrett 30:22 The sweet spot of cholesterol—220 to 240?
Dr. Goodenowe 30:52 Discusses lipid physiology
Dr. Barrett 35:43 What is wrong with mainstream cardiology?
Dr. Goodenowe 37:20 Explains that it is not cholesterol to worry about—it’s the oxidized LDL
Dr. Barrett 40:48 Let’s talk studies
Dr. Goodenowe 41:03 Discusses amyloid and tau proteins
Dr. Goodenowe 47:03 The problem with medical studies
Dr. Goodenowe 54:53 Science is the art of failure
Dr. Barrett 57:38 Plasmalogens and potential role in peripheral neuropathy
Dr. Goodenowe 59:41 Is peripheral neuropathy the neuro muscular version of autism.